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Mutations in the PTEN phosphatase daf-18 increase the ability of nematodes to modulate behavior. The daf-18 null mutation nr2037 restores the ability of males to change behavior to levels comparable with those of mutant hermaphrodites. P < 0.22 (unpaired t-test). nr2037 partially suppresses the learning-defective phenotype of daf-2(e1370) males. P < 0.01 (unpaired t-test). Herm, hermaphrodite. Error bars indicate mean ± standard error.
