Figure 2.—

The role of telomere clustering and “horsetail” nuclear movement in meiotic homolog pairing. (A) Prior to nuclear fusion, telomeres cluster at the SPB (solid circle). In the prophase nucleus, the bouquet promotes alignment of homologs, and horsetail movement facilitates the transition to full pairing. (B) Proposed chromosome configuration in wild-type, dhc1Δ, and bqt2Δ mutant prophase nuclei. Only two of the three chromosome pairs are shown. The stars represent homologous sites on a pair of homologs.