TABLE 1.
Genetic variants at 6p22 and their statistics
| Sample size | No. of variantsa
|
π (%)b | Parameter θ
|
Neutrality testsc
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Population | Singleton | Doubleton | Others | Total | θw | θΠ | Tajima's D | Fu and Li's D | Fu and Li's F | ||
| All samples | 128 | 40 (12.3) | 7 (6.1) | 19 (47.6) | 66 | 0.070 | 12.27 | 7.29 | −1.25 (−1.37) | −5.59** (−1.81) | −4.23** (−1.66) |
| Africans | 40 | 31 (12.0) | 7 (6.0) | 13 (33.0) | 51 | 0.069 | 11.99 | 7.22 | −1.35 (−1.38) | −3.33** (−1.88) | −2.88** (−1.81) |
| Non-Africans | 82 | 11 (6.0) | 1 (3.0) | 18 (21.0) | 30 | 0.064 | 6.03 | 6.66 | 0.32 (−1.38) | −1.65 (−1.87) | −0.99 (−1.74) |
| Asians | 42 | 7 (5.6) | 1 (2.8) | 16 (15.6) | 24 | 0.061 | 5.58 | 6.31 | 0.42 (−1.42) | −0.47 (−1.88) | −0.16 (−1.77) |
| Europeans | 40 | 8 (5.9) | 1 (2.9) | 16 (16.2) | 25 | 0.067 | 5.88 | 6.95 | 0.59 (−1.39) | −0.67 (−1.99) | −0.23 (−1.87) |
**
Significant at the 1% level.
a
The numbers of variants expected from K = θan are given in parentheses.
b
Nucleotide diversity after excluding indels.
c
The critical values were obtained from 5000 simulated samples and are given in parentheses.