Figure 2.—

The zc32 mutation compromises the ability to cope with further mitochondrial stress. Shown are photomicrographs of plates with wild-type (N2) and zc32 mutant animals that developed at the permissive (20°) and nonpermissive temperature (25°) from embryos exposed to mock RNAi or RNAi of genes that induce further mitochondrial stress (spg-7, phb-2, and hsp-60) or ER stress (ire-1). Photographs were taken 84 hr after seeding the RNAi plates with embryonated eggs. The fraction of animals that reached developmental stage ≥L4 (mean ±SEM) is indicated below the images.