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. 2006 Sep 15;2(9):e123. doi: 10.1371/journal.pcbi.0020123

Figure 10. Steady State Concentrations of OCT4–SOX2 and NANOG as Functions of the Signal A + .

Figure 10

There is only one turning point leading to an irreversible bistable switch. At the threshold A + 80, the system switches on and remains on even when the stimulus is removed.