Table 1.
Time (hours p.i.) | ||
24 | 72 | Gene name |
Up-regulated genes | ||
1,57** | -1,16 | Death-associated protein kinase 3 (ZIP-kinase). |
1,32* | 1,42 | HLA class II histocompatibility antigen, gamma chain |
1,56* | 1,30 | HLA class I histocompatibility antigen |
1,25** | 1,04 | Myosin heavy chain, skeletal muscle, adult 1 |
1,33* | -1,15 | Synapse associated protein 1 |
-1,07 | 1,56* | Collagen, type I, alpha 1chain |
1,06 | 1,49* | Collagen, type I, alpha 2 chain |
-1,05 | 1,39* | Phospholipase D family, member 4 |
1,05 | 1,56* | Microtubule-associated protein RP/EB |
-1,14 | 1,28* | Translocon-associated protein, delta subunit precursor |
Down-regulated genes | ||
-1,38* | 1,09 | Cdk inhibitor p21 binding protein |
-1,35* | -1,23 | Cytochrome oxidase subunit III-2 |
-1,39* | -1,15 | Cytochrome oxidase subunit III-3 |
-1,49* | -1,12 | Oxidoreductase UCPA |
-1,22* | -1,02 | Hypoxanthine-guanine phosphoribosyltransferase |
-1,05 | -1,32* | Beclin 1 |
1,23 | -1,21* | Apoptosis inhibitor 5 |
1,04 | -1,48* | Cytochrome P450 2J2 |
-1,01 | -1,35* | Serum/glucocorticoid-regulated kinase |
-1,14 | -1,26** | Lactoferrin |
-1,20 | -1,49* | Alanine-glyoxylate aminotransferase |
-1,07 | -1,65* | Allograft inflammatory factor-1 |
-1,10 | -1,31* | NADH dehydrogenase subunit 5–2 |
-1,06 | -1,34* | Acyl-CoA dehydrogenase 9, mitochondrial |
-1,05 | -1,25* | High affinity immunoglobulin epsilon receptor alpha |
-1,05 | -1,24* | Troponin I, slow skeletal muscle |
-1,18 | -1,79* | Beta enolase |
-1,05 | -1,77* | Telomerase reverse transcriptase |
-1,03 | -1,23* | Coatomer epsilon subunit (Epsilon-COP). |
The expression ratio (normalized log intensity ratio) data at 24 and 72 hours post-injection (p.i.) are shown. Significant differences between control and LPS-injected fish, as analyzed by Student's t-test, are indicated by asterisks (* p < 0.05; ** p < 0.01)