Table 4.
Sensitivities of the Dynalign/LIBSVM classifier, RNAz, and QRNA broken down by percent identity.
| % sensitivity | % specificity | ||||||||||
| % identity range | N | % of real set | Dynalign (P > 0.819) | RNAz (P > 0.789) | QRNA | N | % of negative set | Dynalign (P <= 0.819) | RNAz (P <= 0.789) | QRNA | |
| [0 | 10) | 0 | 0 | N/A | N/A | N/A | 0 | 0 | N/A | N/A | N/A |
| [10 | 20) | 0 | 0 | N/A | N/A | N/A | 0 | 0 | N/A | N/A | N/A |
| [20 | 30) | 3 | 0.0033 | 100.0 | 0.0 | 66.6667 | 49 | 0.0271 | 97.9592 | 100.0 | 95.9184 |
| [30 | 40) | 1337 | 1.4767 | 71.4286 | 34.6298 | 48.6163 | 9037 | 4.9907 | 99.1922 | 97.0233 | 97.8975 |
| [40 | 50) | 22328 | 24.6612 | 63.6465 | 63.1539 | 46.5559 | 85008 | 46.9455 | 99.3612 | 98.8542 | 99.2789 |
| [50 | 60) | 42733 | 47.1984 | 73.0606 | 75.6488 | 56.2469 | 55602 | 30.7061 | 99.2320 | 99.5018 | 99.0306 |
| [60 | 70) | 17346 | 19.1586 | 88.4930 | 92.2461 | 86.0775 | 23952 | 13.2274 | 99.1566 | 99.3028 | 98.8143 |
| [70 | 80) | 4061 | 4.4854 | 94.5826 | 94.5087 | 94.1394 | 4672 | 2.5801 | 97.5813 | 98.4375 | 97.9238 |
| [80 | 90) | 2035 | 2.2477 | 95.5774 | 91.9410 | 93.9066 | 2062 | 1.1387 | 90.8341 | 98.1086 | 96.6052 |
| [90 | 100) | 654 | 0.7223 | 98.4709 | 72.6300 | 59.7859 | 654 | 0.3612 | 60.5505 | 96.7890 | 95.2599 |
| [100 ] | 42 | 0.0464 | 92.8571 | 61.9048 | 11.9048 | 42 | 0.0232 | 61.9048 | 90.4762 | 95.2381 | |
| totals | 90539 | 100.0 | 75.3366 | 81.2854 | 62.0108 | 181078 | 100.0 | 98.9938 | 98.9927 | 98.9905 | |
A comparison of sensitivities of the three ncRNA classification/detection programs within each percent identity range. N is the number of sequences within each range. Probability cutoffs for RNAz and the Dynalign/LIBSVM classifier were selected such that overall specificities for the entire test set match the specificity of QRNA as closely as possible.