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(A) Double staining labeling cytotrophoblasts (cytokeratin 7) and lymphatic endothelial cells (LYVE-1) revealed the close association of the 2 cell types (merged image) in implants maintained for 2 weeks. (B) After 3 weeks, the implant sites contained LYVE-1–positive structures that had the morphological appearance of lymphatic vessels, including the presence of lumens (arrows). Scale bars: 50 μm.
