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Effects of olopatadine on the migration of THP-1 cells induced by S100A12 (a) or RANTES (b). The numbers of cells migrating toward S100A12 (1 μmol/L) or RANTES (10 nmol/L) during 3 h incubation were determined by flow cytometry. The values in panel (a) are means ± SE from 3 independent experiments (n = 9), and those in panel (b) are means ± SE from 2 independent experiments (n = 6). **P < 0.01; ***P < 0.001 (versus control, Dunnett's test). Media, spontaneous migration.
