Table 2.

Comparison of IL-6 and IL-8 levels in supernatants obtained from cultures of different types of fibroblasts. (a) Healthy controls: fibroblasts from normal skin of healthy volunteers; (b) psoriatic skin: fibroblasts from lesional skin of psoriatic patients; (c) noninvolved psoriatic skin: fibroblasts from perilesional skin of psoriatic patients.

Evaluated cytokine	Stimulus	Statistical parameters	Type of fibroblast culture			P level
			Healthy controls	Psoriatic skin	Noninvolved
			(a)	(b)	psoriatic skin (c)
IL-6 (pg/mL)
	Control	range	560–2265	300–3350	215–1550	(a)-(b) P > 0.05
						(a)–(c) P < 0.05
		Me	1444	975	462	(b)-(c) P > 0.05
	IL-8 (0.1 μg/mL)	range	640–3390	465–3225	270–5465	(a)-(b)-(c) P > 0.05
		Me	1225	967	795
	TNF-α (10 ng/mL)	range	3570–94000	2890–32450	850–31880	(a)-(b) P > 0.05
						(a)–(c) P < 0.05
		Me	25890	7738	4105	(b)-(c) P > 0.05
IL-8 (pg/mL)
	Control	range	1540–8690	435–6080	435–6624	(a)-(b)-(c) - P > 0.05
		Me	2924	2803	1238
	IL-8 (0.1 μg/mL)	range	121780–405000	222684–416704	22412–2879913	(a)-(b) P > 0.05
						(a)–(c) P < 0.05
		Me	312550	344399	199391	(b)-(c) P < 0.05
	TNF-α (10 ng/mL)	range	126900–540872	69866–412728	25886–290981	(a)-(b) P > 0.05
						(a)–(c) P < 0.05
		Me	319359	301979	123167	(b)-(c) P < 0.05