Fig. 3.

Living cultures labelled with the dual emission dye, JC1. Mitochondria with low membrane permeability label red; mitochondria with high membrane permeability label green. Bars = 5 µm. (a) Undifferentiated lens epithelial cells showing a high proportion of red labelling in normal mitochondria. (b) A differentiating lentoid showing a very high proportion of green-labelled mitochondria indicating that lentoid differentiation is accompanied by increased mitochondrial membrane permeability. Note that the surrounding undifferentiated epithelial cells are similar to those shown in a.