Table 1.
Morphometric quantitative data of exocytosis in mast cells incubated with 100, 250, 500 and 1000 U mL−1 rhIFN-α 2a for 24 h
| Morphological features | 100 U mL−1 (152 cells) | 250 U mL−1 (138 cells) | 500 U mL−1 (136 cells) | 1000 U mL−1 (127 cells) | Control (194 cells) |
| Resting cells | 93 (61.2) * | 78 (56.5) | 66 (48.5) | 51 (40.1) | 184 (94.8) |
| Focal exocytosis | 8 (5.3) | 10 (7.2) | 14 (10.3) | 14 (11) | – |
| Mild exocytosis | 1 (0.6) | 3 (2.2) | 3 (2.2) | 4 (3.1) | 2 (1.0) |
| Moderate exocytosis | – | – | – | 1 (0.8) | 7 (3.6) |
| Diffuse exocytosis | – | – | – | – | 1 (0.5) |
| Atypical degranulation | 45 (29.6) | 42 (30.4) | 47 (34.5) | 50 (39.4) | – |
| Piecemeal degranulation | 5 (3.3) | 5 (3.6) | 6 (4.4) | 7 (5.5) | – |
*
Numbers in parentheses represent percentages.