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Isometric force recordings showing the effect of 8-phenyltheophylline (8-PT, 10−5 M) on the relaxant response to 5′-N-ethylcarboxamidoadenosine (NECA, 10−7–10−4 M), in U46619 (10−7 M)-contracted pig intravesical ureteral strips. At the end of the experiment, papaverine (PAP, 10−4 M) was added to obtain the maximal relaxation of the ureteral strips. Vertical bar shows tension in g and horizontal bar time in min. Numbers indicate molar concentration in the bath. W: wash out.
