Figure 7.

Comparison between two methods of LTB₄ human whole blood assays. (a) represents plasma LTB₄ levels for both assays and (b) represents the titration curve for RS14203 in both assays. A23187 method: whole blood challenged with 25 μM A23187 for 30 min. Method D: whole blood pre-stimulated with LPS (1 μg ml⁻¹) for 24 h followed by 30 min stimulation with LPS (1 μg ml⁻¹) then a 15 min incubation with fMLP (1 μM). n=3 donors. Both methods were performed in the same donor sample. ^*P<0.05 and ^**P<0.01.