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Cell composition of α- and β-cell populations. Islets from H253 female hemizygotes are double-labelled for β-gal (fluorescein) and the appropriate hormone (TRITC/Texas Red). Insulin+β-cell populations and glucagon+α-cell populations are both of heterogeneous β-gal+/β-gal− cell composition. (A) Glucagon. (B) Insulin. Scale bar = 50 µm.
