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‘Dumbbell’ islets in histological sections. (A,B) Paraffin sections of X-gal-stained mosaic female pancreas immunoperoxidase-stained for glucagon. (C) Frozen section of mosaic female pancreas immunofluorescence-stained for β-gal (fluorescein) and glucagon (Texas Red). Note neck of glucagon+ cells (arrows). Scale bar = 100 µm.
