Table 1.

Diagnosis, age and sex distribution of the study sample of 32 ISS patients and 11 unaffected individuals. Nine of the 32 ISS patients had both pre- and postoperative MRIs; one ISS patient had only a postoperative scan

Diagnosis	Age (weeks)	N
Samples at Age A
Preoperative sagittal synostosis	10–43	28 (23M, 5F)
Unaffected	14–50	6 (4M, 2F)
Samples at Age B
Preoperative sagittal synostosis	72–105	3 (3F)
Postoperative sagittal synostosis	68–116	10 (8M, 2F)
Unaffected	72–107	5 (1M, 4F)