Fig. 5.

Putative human MIP equivalent as assessed with fMRI (Grefkes et al. 2004). (A) Electrophysiological MIP experiments in the macaque brain (Eskandar & Assad, 2002). MIP neurons were recorded while the monkey performed a visuomotor joystick task. MIP neurons responded irrespective of whether a visual movement feedback was present on the video screen but much less when joystick movements were absent (playback trials). (From Eskandar & Assad, 2002, with permission.) (B) Adopted protocol used for the fMRI study with human subjects (Grefkes et al. 2004). Fixating volunteers were asked to guide the black square from the white to the black circle using an MRI-compatible joystick. (C) Visually directed joystick movements (with or without movement feedback) elicited significantly higher activity in medial IPS than the control conditions consisting of stereotype-intransitive joystick movements. (Adapted from Grefkes et al. 2004, with permission.)