Fig. 2.

NG2-positive OPCs react to injury. Small stab wounds were made into the cerebellum of adult rats and the tissue was stained with anti-NG2 antibodies at the indicated survival times. By 2 days post-injury, many small intensely positive cells appear along the walls of the lesion cavity. At 4 and 10 days post-injury, the NG2-expressiong cells have formed small plaques at the injury site. These plaques correspond to the glial scar.