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. 1999 Sep;128(2):451–457. doi: 10.1038/sj.bjp.0702781

Figure 1.

Figure 1

Relaxations of the detector ring induced by iohexol, iodixanol and dextran 80 in cascade bioassay, plotted as a function of the viscosity of the buffer perfusing the donor rabbit aorta. Increasing concentrations of each agent evoked progressive relaxation of the recipient aortic ring. Inclusion of L-NAME (100 μM) in the buffer had no effect on relaxations evoked by iohexol or iodixanol, but significantly attenuated those induced by dextran. *Denotes P<0.05 for dextran in the presence and absence of L-NAME.