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Tracings of the response to acetylcholine as affected by progesterone and ketoconazole in monkey lingual artery strips with intact endothelium in the presence of indomethacin (1 μM) and L-NOARG (0.1 mM). Two strips were obtained from the same monkey and partially contracted with PGF2α. Concentrations of acetylcholine from 8 to 5, 10 nM, 100 nM, 1 μM, and 10 μM, respectively. PA represents papaverine (0.1 mM) that produced the maximal relaxation.
