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Mechanism of acetylcholine-induced dilation of arterioles adjacent to the sciatic nerve. Arterioles from diabetic rats were constricted with U46619 and treated with LNNA or KCl alone prior to application of graded doses of acetylcholine. Acetylcholine induced dilation was significantly decreased by LNNA or KCl alone. #P<0.05 vs diabetic. Diabetic (n=8), LNNA (n=3) and KCl (n=3).
