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Representative isometric tension tracings of a longitudinal muscle strip of a rat gastric fundus showing the control (A), the effect of 10 μM guanethidine (B) and of 3 μM nadolol in combination with 3 μM phentolamine (C) on the relaxation induced by 30 μM nicotine. These experiments were performed during a 0.1 μM 5-HT-induced contraction in the presence of 1 μM atropine. The degree of the nicotine-induced relaxation is indicated by the double-headed arrow.
