Effects of flavonoids on the growth (A) unstimulated and (B) EGF-stimulated A431 cells. Cells were treated with flavonoids (20 μM) and/or EGF (10 nM) for 24 h. Cell numbers of the culture were then determined. Each bar represents the mean (±s.e.mean) of six replicates from a representative experiment. Three separate experiments were performed and all showed similar results. The mean cell number of control groups was 6.08×105. Con, control; Lu, luteolin; Qu, quercetin; Gen, genistein; Tax, taxifolin; d-Cat. d-catechin; Nar, naringenin; Kae, kaempferol; Wog. wogonin.