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Extracellular concentrations of NA in the frontal cortex of rats given saline (Sal+Sal), 15 mg kg−1 reboxetine (Reb+Sal), saline+1 mg kg−1 idazoxan (Sal+IDZ) and reboxetine+idazoxan (Reb+IDZ). Inset: AUC calculated from 0–180 min. Each group is the mean±s.e.mean of 6–7 rats. *P<0.05 vs Sal+Sal; °P<0.05 vs Reb+Sal; #Fint. P<0.05 (two-way ANOVA). The arrows indicate drug injection.
