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Effect of IL-4 gene depletion (A) and anti-IL-4 (B) monoclonal antibody treatment on contact hypersensitivity (CH) caused by repeated applications of DNFB. Each column consists of the mean±s.e.mean of six or seven animals. **(A) Significant difference from DNFB treated wild type mice at P<0.01. (B) Significant difference from rat IgG and DNFB treated mice.
