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. 2000 Jan;129(2):231–234. doi: 10.1038/sj.bjp.0703067

Figure 1.

Figure 1

Dose-dependent protective effect of curcumin against ADR-induced microsomal and mitochondrial lipid peroxidation. Microsomes or mitochondria were incubated with NADPH-generating system or NADH, respectively in the absence or presence of 100 μM ADR and lipid peroxidation was measured by the thiobarbituric acid method. Curcumin (1, 10 or 100 μM) was added to incubation mixtures before adding NADPH-generating system or NADH. Data are mean±s.d. of six observations. *Significantly (P<0.001) higher than all groups; †significantly (P<0.05) lower than ADR; ‡significantly (P<0.01) lower than ADR; ≈rcub;significantly (P<0.001) lower than ADR, but not significant compared to controls.