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Intracellular pH measured in BCECF-loaded Caco-2 cell monolayers. The effect on pHi of exposure to 20 mM GABA (at pH 7.4 and pH 5.5) at either the apical (A) or basolateral (B) membranes of Caco-2 cell monolayers in the presence of extracellular Na+. Addition of GABA is indicated by the filled boxes. A representative trace of five separate experiments.
