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Effect of L-NOARG (10−4 M, a), aminoguanidine (AG, 10−4 M, b) and 1400 W (10−6 M, c) with or without L-arginine (L-ARG, 10−4 M) and D-arginine (D-ARG, 10−4 M) on VIP-induced relaxation in isolated smooth muscle cells of the guinea-pig gastric fundus. Values are mean±s.e.mean from n=6. ***P<0.001, significantly different from cells treated with VIP. +++P<0.001, significantly different from cells treated with VIP and NOS inhibitor.
