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Effect of increasing concentrations of SQ 22,536 (10−9–10−6 M) on the relaxant effect of VIP (10−6 M), SNP (10−6 M) and isoprenaline (ISO, 10−4 M) in isolated smooth muscle cells of the guinea-pig gastric fundus. Values are mean±s.e.mean from n=6. *P<0.05, **P<0.01, ***P<0.001, significantly different from cells treated with VIP, SNP or ISO.
