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Rat isolated vagus nerve: (a) experimental record showing depolarization induced by KCl and the prostacyclin analogue cicaprost, (b) log concentration-response curves for four prostacyclin analogues, the EP1/EP3 agonist sulprostone, and the selective 5-HT3 agonist 2-methyl 5-HT, and (c) log concentration-response curves for cicaprost and three non-prostanoid prostacyclin mimetics. Numbers of preparations are shown in brackets; vertical bars are s.e.means.
