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The effect of β-adrenoceptor antagonists on relaxation induced by isoprenaline in rat thoracic aortic rings preconstricted with noradrenaline (1 μM). Results are expressed as percentage relaxation of tone induced by noradrenaline. Values are mean±s.e.mean of n observations (a) Effect of propranolol (0.3 μM) (n=19–37). (b) Effect of CGP 20712A (0.1 μM) and ICI 118551 (0.1 μM) (n=6).
