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The effect of bupranolol (5–30 μM) on β-adrenoceptor agonist-induced relaxation in rat thoracic aortic rings preconstricted with noradrenaline (1 μM). Results are expressed as percentage relaxation of tone induced by noradrenaline. Values are mean±s.e.mean of n observations. (a) Effect of bupranolol (5–30 μM) on relaxation induced by isoprenaline (in the presence of 0.3 μM propranolol) (n=4–9). (b) Effect of bupranolol (5–30 μM) on relaxation induced by CGP 12177A (n=3–8).
