Concentration-response of chloroethylclonidine-induced contraction in caudal arteries from Wistar, WKY and SHR rats. Arterial rings were incubated with (±)-propranolol and rauwolscine (100 nM, each) prior to and during chloroethylclonidine (1–100 μM) exposure. Contraction is expressed as percentage of maximal noradrenaline effect (2.36±0.09, 1.15±0.05 and 0.73±0.04 g for Wistar, WKY and SHR, respectively). Results represent the means±s.e.mean of 4–6 different animals.