Figure 5.

Effect of chloroethylclonidine on the concentration-response curves to noradrenaline in caudal arteries from Wistar, WKY and SHR rats. Arterial rings were incubated with increasing concentrations of chloroethylclonidine, after 45 min arteries were extensively washed and then subjected to a concentration-response curve to noradrenaline. Results are expressed as percentage of maximal noradrenaline-induced contraction and represent the means±s.e.mean of 4–6 different animals. The effect of 1 μM chloroethylclonidine is omitted for clarity.