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. 2000 Feb;129(4):811–819. doi: 10.1038/sj.bjp.0703107

Figure 2.

Figure 2

Effect of (a) 67 mM extracellular K+ (high [K+]o), (b) apamin (0.3 μM) and (c) ouabain (1 μM) on endothelium-dependent relaxations to BK in the absence and presence of L-NOARG (100 μM) in rings of bovine coronary artery contracted with U46619. Values (mean±s.e.mean from n=5–6 experiments) are expressed as a percentage reversal of the initial U46619-induced contraction. (*P<0.05 and **P<0.001) and (+P<0.001) indicate that pEC50 and Rmax values, respectively were significantly different from those obtained in control tissues (for Tukey-Kramer's t-statistic after one way ANOVA).