Effects of occlusion of the LAD in dogs, pretreated with either saline (controls), the ACE/NEP inhibitor Z13752A (128 μg kg−1 min−1 i.v.), the antagonist of bradykinin at B2 receptors (icatibant 0.3 mg kg−1) or combination of both drugs. Values are means±s.e.mean of the maximum change (3–5 min) after occlusion