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. 2000 Mar;129(5):893–900. doi: 10.1038/sj.bjp.0703132

Figure 3.

Figure 3

Current-voltage relationship of ICa,L in the absence and presence of 50 μM Pro. A 1-s preconditioning pulse of −40 mV from HP of −80 mV was followed by various depolarizing pulses (−30∼+60 mV, voltage increment 10 mV, duration 300 ms) to elicit ICa,L at 0.2 Hz. (A) Original recordings of ICa,L at different voltages under control condition (left), after exposure to 50 μM Pro, and upon 2-min washout. (B) Average data on effects of Pro on ICa,L over the entire voltage range. *P<0.05, †P<0.01 vs controls, n=7.