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Percentage changes in rabbit femoral artery pressure (mean±s.e.mean) from baseline, in response to increasing doses of injected isoprenaline, before and after administration of 30 nmol kg−1 CGP 20712A or 10 nmol kg−1 ICI 118551. Isoprenaline responses were unaffected by CGP 20712A, but were abolished by ICI 118551 (P<0.0001).
