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Relaxations induced by exogenous NO infused for 10 min before and in the presence of 10−5 M LY83583 (b) and its solvent ethanol (a), 10−4 M hydroxocobalamin (HC, c) and 10−4 M hydroquinone (HQ, d). The response measured at 1, 2, 3, 5, 8 and 10 min of infusion was expressed as a percentage of the maximum relaxation obtained during the NO-infusion before administration of the drugs. Means±s.e.mean of n=6 are shown. *P<0.05; **P<0.01; ***P<0.001: significantly different versus before.
