Figure 3.

(A) The effects of NSD 1015 (25 mg kg⁻¹ i.p.) or vehicle pretreatment on locomotor activity and disability scores induced by L-DOPA (5–18 mg kg⁻¹ s.c.) and carbidopa (12.5 mg kg⁻¹ i.p.) accumulated over 2 h (n=4) in MPTP-lesioned marmosets. (B) The effects of NSD-1015 (25 mg kg⁻¹ i.p.), in the absence of carbidopa on locomotor activity and disability scores induced by L-DOPA (5–18 mg kg⁻¹ s.c.) accumulated over 2 h (n=4) in MPTP-lesioned marmosets. The data are expressed as mean±s.e.mean ^*P<0.05 vs saline pretreatment group.