Figure 3.

Cumulative concentration-effect curves described in terms of (a,c) increase in airway resistance (%R_L) and (b,d) decrease in dynamic compliance (%C_dyn) from basal levels in response to aerosolized histamine prior to antigen challenge and following antigen challenge in animals treated with either heparin (5000 U.ml⁻¹) or heparin vehicle (chlorocresol, 0.15%), prior to (a,b) and following (c,d) antigen challenge. Data presented as the mean±standard error of the mean from 12 and 10 animals respectively.