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Immunohistochemistry in the isolated perfused rat liver experiments. On liver biopsies taken 5 and 25 min after adding xenogeneic serum, immunofluorescence studies showed the deposition of human IgM (a) and factor Bb (b) along sinusoidal endothelial cells (patterns obtained from one representative experiment out of six). After adding decomplemented human serum, only IgM deposits were observed (c). Bar=10 μm. Deposits are indicated by arrows.
