Figure 6.
Effect of dexketoprofen (1 mg kg−1, i.v.) or NS-398 (2 mg kg−1, i.v.) on cystometries performed in CYP (150 mg kg−1, i.p., 48 h before)-treated rats 3 h after bladder catheter insertion and 2 h after having started cystometries. (A) Represents the effect on the micturition frequency. (B) The effect on the pressure threshold for triggering micturition contractions. (C) The effect on the minimal pressure. (D) The effect on the mean amplitude of micturition contractions. Fisher's LSD test: dexketoprofen *P<0.05 vs time-matched vehicle-treated group and vs their own basal values (time 0). Each point and bar represents mean±s.e.mean of 12 experiments.