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. 2000 May;130(2):359–366. doi: 10.1038/sj.bjp.0703317

Figure 6.

Figure 6

Relaxant responses to two boli of exogenous NO (10−5 M), applied with an interval of 8 min, in the presence of HX (3×10−4 M) / XO (64 mu ml−1) alone or plus one of the antioxidants indicated. The first (1) and second (2) phase of the relaxant response to NO in the presence of HX/XO is shown. The relaxations are expressed as a percentage of the response to the same stimulus before administration of the drugs under study. All results are the means±s.e.mean of 6–7 strips from different animals. *P<0.05; **P<0.01; ***P<0.001: significantly different from the response in the presence of HX/XO alone (unpaired t-test). ASC=ascorbic acid; GSH=glutathione; α-TOC=α-tocopherol; UA=uric acid; SOD=superoxide dismutase; BILI=bilirubin; HX=hypoxanthine; XO=xanthine oxidase.