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(A) Chemical structure of JTV-519 (JT). (B) Representative recording of contractile tension during 10 min of JT (0.3 μM) application, followed by washout. The arrow indicates the point where the maximal decrease of contraction was observed (approximately 5 min after washout of JT). (C) Summarized data for the per cent decrease of dTension by JT and diltiazem (DIL).
