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. 2000 Jun;130(4):767–776. doi: 10.1038/sj.bjp.0703373

Figure 5.

Figure 5

Effects of 5-HD with or without JT on developed tension before and during I/R. (A) Representative recordings of contractile tension in the control group, the JT (1.0 μM) group, and the JT (1.0 μM) plus 5-HD (400 μM) group before and during I/R. (B) Per cent change of the dTension before and during I/R in the control group, the JT group, the 5-HD group, and the JT+5-HD group. The data of the control group and the JT group (1.0 μM) were the same as shown in Figure 2B). The per cent recovery of the dTension in the JT+5-HD group measured at 60 min of reperfusion (34±6%, n=4) was comparable to that in the control group, suggesting that the treatment with 5-HD completely antagonized the effect of JT. The per cent recovery of the dTension in the group with 5-HD alone, measured at 60 min of reperfusion (33±7%, n=4) was the same as that in the control group. *P<0.01: significant difference vs JT (1.0 μM) group.