Figure 4.

Zn²⁺ reduces Cu²⁺-block in a concentration dependent manner. (A) Real-time-scheme of experiments; upper line: Cu²⁺, lower lines Zn 10−300 nM for 10 s and GABA 2 μM for 1 s. data points in the dose response curve are normalized to control GABA responses and represent the mean responses of five cells. The data are fitted by equation 2 with EC₅₀=72±13 μM, n=1.35±0.3.