Figure 3.

Effect of the vehicle (0) and TKI injected intraperitoneally (13.6–136 μmol kg⁻¹), in (A) or subcutaneously (41–410 μmol kg⁻¹), in (B) on the formalin-induced (50 μl 1.2% formaldehyde in PBS) first (neurogenic pain) and second (inflammatory pain) phases of nociception in mice. Positive control mice were treated orally with indomethacin (Ind, 28 μmol kg⁻¹, A). The columns and vertical bars are means±s.e.mean of 8–9 animals. ^*Different from vehicle-treated mice (P<0.05).