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. 2000 Jul;130(5):1174–1182. doi: 10.1038/sj.bjp.0703412

Figure 6.

Figure 6

The effects of GAP-27 and 18-α-glycyrrhetinic acid in pressurized arteries. (a) Application of the gap junction inhibitor Gap-27 (300 μM) into lumen of the pressurized artery depressed ACh dilatations, such that only a small, transient dilatation remained. The gap in the data trace shows where Gap-27 was being loaded into the lumen. The bar graph shows mean data (n=4). *Shows significance (P<0.05) compared to control. (C) The gap junction inhibitor, 18-α-glycyrrhetinic acid (100 μM) in the superfusate depressed ACh dilatations, but not dilatations to high [K+]o. Mean data (n=3). *Shows significance compared to control.